Tuesday, February 10
18:00-18:45 Registration
19:00 Welcome and Opening Lecture
Sponsored by DIGNA Biotech
Chairman: Juan J. Calvete
19:30-20:00 Good News for MALDI - The Advent of Second Generation Matrices
Prof. Michael Karas, Johann Wolfgang Goethe University
20:00-20:30 Reaction Kinetics in the MALDI Plume: The Yield of Positive versus Negative Peptide Ions
Prof. Franz Hillenkamp, University of Muenster
21:00 Welcome reception
Wednesday, February 11
Session 1: Quantitative Proteomics
Sponsored by Waters
Chairman: Jesús Vázquez, Deborah Penque
Plenary Sessions
09:00-09:30 Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) as a Tool in Cancer Research
Dr. José Luis Luque. Spanish National Cancer Research Center
09:30-10:00 Isotope-Coded Protein Labelling (ICPL) as a tool for the quantitative analysis of a bacterial proteome
Dr. Alberto Paradela. Biotechnology National Center
10:00-10:30 Peptide fractionation for proteomic studies
Dr. Gabriel Padrón. Center for Genetic Engineering and Biotechnology, La Havana, Cuba
Oral Communications
10:30-10:45 Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17
Francesc Canals. Vall d’Hebron University Hospital
10:45-11:00 Label-free quantification based on data independent acquisition mass spectrometry
Miren Josu Omaetxebarria. University of the Basque Country
11:00-11:15 Identification and Quantification of proteins from Methylophaga Thiooxidans and Methylocella Silvestris using label-free LC/MS
Joanne B. Connolly. Waters
11:15-11:45 Coffee Break
Session 2: Posttranslational Modifications
Sponsored by Agilent Technologies
Chairman: David Andreu, Gabriel Padrón
Plenary Sessions
11:45-12:15 Quantitative phosphoproteomics: a powerful tool to define kinase-substrate relationships
Dra. Judit Villén, Harvard Medical School, Boston
12:15-12:45 Proteomic analysis of S-nitrosated proteins
Dr. Antonio Rodriguez Ariza. Reina Sofia University Hospital of Cordoba
12:15-13:15 Understanding by proteomics the cellular trafficking defect of a disease associated mutant protein
Dra. Deborah Penque. Instituto nacional de Saudé Dr. Ricardo Jorge, Lisboa.
Oral Communications
13:15-13:30 Quantitative analysis of protein glycation in clinical samples
Feliciano Priego, University Medical Center, Geneva, Switzerland
13:30-13:45 New microfluidic chip targeting phosphoproteomes
Dayin Lin, Agilent Technologies
14:00-15:00 Lunch
15:00-16:00 Poster Session
HUPO Initiatives
Sponsored by Genoma España and Thermo Scientific
Chairman: José María Mato
Liver
16:00-16:30 The Insight into the Human Liver Proteome
Prof. Fuchu He. Fudan University, Shanghai, China
Brain
16:30-17:00 Characterisation of the Autoimmune Antibody Repertoire of Parkinson’s Disease Patients by Systematic Screening of Protein Arrays
Prof. Helmut E. Meyer. Medizinisches Proteom-Center, Ruhr-Universität Bochum, Germany
17:00-17:30 Coffee Break
HUPO Initiatives-2
Sponsored by Genoma España and Thermo Scientific
Chairman: José María Mato
PSI
17:30-18:00 Annotating the Human Proteome
Prof. Rolf Apweiler. EMBL/EBI, Hinxton, UK
Thursday, February 12
Session 3: Bioinformatics in Proteomics
Sponsored by Promega Biotech Ibérica
Chairman: Juan Pablo Albar, Andrea LLera
Plenary Sessions
09:00-09:30 Application of a novel statistical model for quantitative proteomics by 18O labeling to the study of VEGF-induced angiogenesis in vascular endothelial cells
Pablo Martínez-Acedo. Severo Ochoa Molecular Biology Center
09:30-10:00 Properties of Average Score Distributions of SEQUEST: The Probability Ratio method
Pedro Navarro. Severo Ochoa Molecular Biology Center
10:00-10:30 The neuropeptidome of rhodnius prolixus brain
Dr. Rolando Rivera Pomar. Centro Regional de Estudios Genómicos, Buenos Aires, Argentina
Oral Communications
10:30-10:45 Storing, reporting and comparing proteomics experiments using the miape generator tool
Salvador Martínez, ProteoRed – National Center for Biotechnology-CSIC
10:45-11:00 Proteopathogen, a protein database to study host-pathogen interaction
Vital Vialas, Complutense University of Madrid
11:00-11:15 HaloLink™ Protein Arrays for Functional Analysis of Proteins
Patricia Bresnahan, Promega Biotech Ibérica
11:15-11:45 Coffee Break
Session 4: Protein Interactions and Protein Arrays
Sponsored by Sigma-Aldrich
Chairman: Jean Charles Sánchez
Plenary Sessions
11:45-12:15 Real-time and Label-free Biomolecular Interactions Analysis using Self-assembled Protein Microarrays and Surface Plasmon Resonance Imaging
Dr. Manuel Fuentes. Harvard Institute of Proteomics, Harvard Medical School.
12:15-12:45 Novel approaches to the characterization of metastasis in colorectal cancer
Dr. Ignacio Casal. Spanish National Cancer Research Center.
12:15-13:15 Deciphering the interactome of p8, a protein related to tumor progression
Dra. Silvia Moreno. Universidad de Buenos Aires, Argentina
Oral Communications
13:15-13:30 High-Mass MALDI ToF Mass Spectrometry and Chemical Cross-linking for Interaction Analysis
Alexis Nazabal, Swiss Federal Institute of Chemistry
13:30-13:45 Lectin-sugar interactions deciphered by SPR-MS and CREDEX-MS
Carmen Jimenez, Pompeu Fabra University
13:45-14:00 Monitoring in vivo protein-protein interactions by coupling bimolecular fluoresecence complementation (BIFC) and flow cytometry
Montse Morell. Universidad Autónoma de Barcelona
14:00-15:00 Lunch
15:00-16:00 Poster Session
Session 5: Human Proteomics and Biomarkers
Sponsored by Bio-Rad
Chairman: Concha Gil, Jonas Perales
Plenary Sessions
16:00-16:30 Proteomics and Metabolomics of human atherosclerotic arteries
Dr. Fernando Vivanco. Jiménez Díaz Fundation
16:30-17:00 Proteomics in obesity research
Dra. Silvia Barceló. Instituto Aragonés de Ciencias de la Salud
17:00-17:30 Using proteomics to unravel the molecular pathway of sparc-mediated tumorigenicity
Dra. Andrea Llera. Fundación Instituto Leloir, Buenos Aires, Argentina
17:30-18:00 Detection of novel biomarkers of liver cirrosis by proteomic analysis
Prof. Helmut E. Meyer. Medizinisches Proteom-Center, Ruhr-Universität Bochum, Germany
Oral Communications
18:00-18:15 Identification of replication-competent HSV-1 Cgal+ strain signalling targets in human hepatoma cells by functional organelle proteomics
Enrique Santamaría, Centre for Applied Medical Research (CIMA), University of Navarra
18:15-18:30 Genomic and proteomic analyses reveal a relationship between wnt pathway genes, oxidative stress metabolism and vascular calcification
Pablo Román, University Hospital of Asturias
18:30-18:45 BioCore study (“Biomarkers of Coronary Events”): from sampling to discovery of plasma biomarkers by SELDI-TOF MS and 2DE
Olivier Meilhac. Hôpital Xavier Bichat - PARIS. Bio-Rad
18:45-19:00 Coffee Break
19:00-20:00 Seprot Awards
Sponsored by Bruker
Seprot Award Session
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites
Enrique Calvo, Spanish National Centre for Cardiovascular Research
20:00-20:45 Seprot General Meeting
21:00 Congress Dinner
Please, contact organizing committee for any special eating habits (gluten intolerance, special allergies…)
Friday, February 13
Session 6: Animal, Plant and Microbial Proteomics
Sponsored by Applied Biosystems
Chairman: Jesús V. Jorrín, Silvia Moreno
Plenary Sessions
09:00-09:30 Top-down and bottom-up quantitative proteomic approaches to characterize the development of grape berry tissues
Dr. Roque Bru. University of Alicante
09:30-10:00 Proteomic identification of s-nitrosylated proteins in arabidopsis thaliana in response to pathogen infection
Dra. Ana María Maldonado. University of Cordoba
10:00-10:30 Using DM43 and DM64, two antitoxins from Didelphidae, to study the snake venom sub-proteomes
Dr. Jonas Perales. Oswaldo Cruz Foundation, Brazil
Oral Communications
10:30-10:45 Combined proteomic and transcriptomic analysis identifies differentially expressed pathways associated to Pinus Radiata needle maturation
Luis Valledor, Univesity of Oviedo
10:45-11:00 Quantitative proteomics analysis of lymph nodes from pigs infected by porcine circovirus type 2 (PCV2) by 2-DE, 18O/16O labeling and linear ion trap mass spectrometry
María Ramirez, University of Córdoba
11:00-11:15 Intelligent Use of Retention Time for Higher Order Multiple Reaction Monitoring Multiplexing
Antonio Serna, Applied Biosystems
11:15-11:45 Coffee Break
Closing Lecture
Sponsored by DIGNA Biotech
Chairman: Fernando J. Corrales
11:45-12:45 Never give up your dreams
Prof. Peter Roepstorff. University of Southern Denmark
12:45-13:15 4th Seprot and 3rd LAHUPO Meeting Venue
13:15 - Farewell