Primary Progressive Apraxia, Acalculia & Agraphia without Alexia
Top, patient attempt to write to dictation the statement in Spanish in the middle of the frame ("it's cold") that he is able to copy at the bottom (but the R becomes an A)
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Primary Progressive Apraxia, Acalculia & Agraphia without Alexia |
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| 72-year-old former businessman with a two-year history | ||
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Top, patient attempt to write to dictation the statement in Spanish in the middle of the frame ("it's cold") that he is able to copy at the bottom (but the R becomes an A) |
The area of the frontal and parietal association cortex expected to be affected has been marked with a grid | FDG PET |
| Note the severe agraphia. The patient could read correctly and had no aphasia | Association cortex for the upper extremity is responsible for hand praxis and writing. Perisylvian cortex, responsible for similar functions related to the mouth region, were expected to be normal, as indeed illustrated by the FDG PET | Note the decreased perfusion of the association cortex of the frontal and parietal lobes (arrow), but primary cortex and cortex for the mouth region are normal |