University of Navarra-Master's Program in Biomedical Research

Research Projects

Assignment of Research Projects for 2010-2011

Upon registering for the Master's program, each student must indicate the area of research in which he or she would prefer to work during the End of Master's Project, and must choose a research project from among those offered. Each director will receive the list of students who have chosen his or her project, and will select a candidate.

For the rest of the students, the Master's Direction Commission will assign them a project trying to take into account their preferences. Given the limited number of projects, it is not possible to guarantee that the research project which will be finally assigned will correspond to the area indicated by the student.

Assignment of Research Projects

· Project 1 - Generation of mutants deficient in metabolic pathways involved in Brucella pathogenicity
· Project 2 - Generation of mutants deficient in metabolic pathways involved in Brucella pathogenicity
· Project 3 - Study of the molecular mechanisms related to alterations of memory and neural degeneration in Alzheimer's Disease (AD)
· Project 4 - Evaluation of the use of peptides derived from the protein TGFBI as possible antitumor agents
· Project 5 - Development of new idiotypic vaccination strategies for the treatment of follicular lymphoma in preclinical models
· Project 6 - Impact of chronic inflammatory processes in the appearance and development of Alzheimer's disease
· Project 7 - Strengthening of antibiotics against multiresistant bacteria via the combined action of enzymatic inhibitors and permeabilizing peptides
· Project 8 - Genetic profile of tumorous stem cells of brain tumors
· Project 9 - Blockage of the mechanisms of immunosuppresion in order to increase the effectiveness of vaccination against cancer and chronic infectious diseases
· Project 10 - Evaluation of diagnostic techniques for the detection of human infection by Legionella spp
· Project 11 - Characterization of the oncogenic potential of mutations which affect the Jak2 FERM domain
· Project 12 - Study of the alterations in vascular traffic of the cholangiocytes in AE2-deficient mice
· Project 13 - Mechanisms of flavonoid action as antifibrogenic agents
· Project 14 - Study of the expression of the incretinic hormone (GLP-1) in the intestines of NOD mice of 12 and 28 weeks and its relationship with the neogenesis and apoptosis of pancreatic beta cells
· Project 15 - Alterations in insulin as a model of Alzheimer's disease
· Project 16 - Acquisition of chemoresistance in breast cancer associated with a hyperactivation of the Sonic Hedgehog-Gli signal pathway
· Project 17 - Simultaneous targeting cell cycle and apoptosis pathways to cure mantle cell lymphoma
· Project 18 - Interactions of the EGFR system in the inflammation-fibrosis-cancer axis in the liver: identification of new mechanisms of progression of the lesion and therapeutic targets
· Project 19 - Use of RNA interference on the basis of a Flip-Flop system in order to inhibit the expression of the Hepatitis B virus
· Project 21 - Development of new specific therapies in order to prevent myocardial infarction and cerebral infarction
· Project 22 - Role of the glutamate and GABA systems in depression: genetic-environmental risk factors
· Project 23 - Study of mechanisms which strengthen the effectiveness of anti-CD20 antibodies in the treatment of follicular lymphoma
· Project 24 - Development and evaluation of a viral vector for the treatment of cancer
· Project 25 - Development of mice with "humanized" livers